Libros
Rony Seger · Humana Press, 2010
Mitogen-activated protein (MAP) kinase (MAPK) cascades are key signaling components that govern essentially all cellular processes evoked by any type of stimulation, and it has been well established that the malfunctioning of these cascades leads to various diseases including cancer, autoimmunity, and diabetes. In MAP Kinase Signaling Protocols, Second Edition, expert researchers fully update the popular first edition the key techniques used in the study of MAPK signaling cascades in various cellular contexts. This thorough volume explores essential topics such as activation and function of components of the MAPK signaling cascades, the study of MAPK cascades as transmitters of membranal receptor signals, structure-function relationships of MAPKs, studies on the regulation of MAPK cascades, the use of lower organisms, animal models, and human genetics in the study of MAPKs, as well as the study of MAPKs in specific systems and diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters includes introductions to their respective subjects, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, MAP Kinase Signaling Protocols, Second Edition aims to facilitate the study of MAPKs and allow for quicker progress in our knowledge of many vital cellular processes as well as devastating diseases.
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Universitario · En inglés
Valerie W. Hu
Springer, 1994
Regulators of the Cell Cycle: Protein Phosphorylation and the Regulation of Key Events in Oocyte and Egg Cell Cycles; J.L. Maller. Control of Cell Proliferation: Extracellular Signal-Regulated Protein Kinases 1,2, and 3; D.J. Robbins, et al. Cell Cycle Control of Gene Expression and Repair: Histone Gene Transcription…
Universitario · En inglés
T. S. Work, Marc Hubert Victor van Regenmortel y otros
Elsevier Science, 2000
The book describes most of the methods that are currently used in metastasis research. Both in vivo and in vitro protocols are illustrated, so that the metastatic process can be either analysed as a whole, or single events addressed separately. Each method is described in the frame of the metastatic process, therefore…
Universitario · En inglés
Jonathon Howard
Sinauer Associates, 2001
This text is for biology, biochemistry and chemistry students who want to learn about the principles of protein mechanics and how it applies to the morphology and motility of cells. Understanding how motors and the cytoskeleton operate requires mechanical concepts such as force, elasticity and damping. Introductory…
Universitario · En inglés
Leslie Wilson, John J. Correia
Elsevier/Academic Press, 2010
There continues to be intense interest in the microtubule cytoskeleton, the assembly, structure and regulation of microtubules and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven…
Universitario · En inglés
Bryant/Franis
Taylor & Francis, 2008
The Eukaryotic Cell Cycle gives an overview of the stages of the eukaryotic cell cycle, as well as discussing important experiments, research, organisms of interest and findings connected to each stage of the cycle and the components involved in these. This volume, written by respected researchers, gives an excellent…
